Chapter 70: Cyclooxygenase Inhibitors: Nonsteroidal Anti-inflammatory Drugs and Acetaminophen

Chapter 70: Cyclooxygenase Inhibitors: Nonsteroidal Anti-inflammatory Drugs and Acetaminophen

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

1. The nurse is teaching a pharmacology class and is differentiating between aspirin and other cyclooxygenase inhibitors. The nurse would correctly identify which of the following as a unique characteristic of aspirin, not found in other cyclooxygenase inhibitors?

a.	Aspirin promotes gastric bleeding.
b.	Aspirin irreversibly inhibits cyclooxygenase.
c.	Aspirin promotes platelet synthesis.
d.	Aspirin enhances prostaglandin synthesis.

 

 

ANS:   B

Aspirin is the only cyclooxygenase inhibitor that irreversibly inhibits cyclooxygenase.

Aspirin and other cyclooxygenase inhibitors promote gastric bleeding, therefore this is not a unique side effect of aspirin.

Aspirin and other cyclooxygenase inhibitors inhibit platelet aggregation; they do not promote platelet synthesis.

Aspirin and other cyclooxygenase inhibitors inhibit rather than enhance prostaglandin synthesis.

 

DIF:    Cognitive Level: Application             REF:    p. 830

TOP:    Nursing Process: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

2. A nurse counsels parents about antipyretic choices for an 8-year-old with influenza. Which statement, made by one of the parents, best demonstrates understanding of an appropriate antipyretic choice?

a.	Acetaminophen is toxic to the liver.
b.	Ibuprofen may increase fever in children younger than age 10.
c.	Sponge baths are the best option.
d.	Aspirin may increase the risk of Reye’s syndrome.

 

 

ANS:   D

Aspirin increases the risk of Reye’s syndrome in children; this statement demonstrates understanding of the correct antipyretic choice.

Acetaminophen is toxic to the liver, but this is not what the question asks.

Ibuprofen does not increase fever; it is considered an antipyretic as well as an analgesic.

Sponge baths could be used as adjunctive therapy, but not as the only option.

 

DIF:    Cognitive Level: Application             REF:    p. 831

TOP:    Nursing Process: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

3. A patient who takes daily doses of aspirin is scheduled for surgery in the next few days. The nurse should advise the patient to

a.	continue to use aspirin as scheduled.
b.	stop using aspirin immediately.
c.	stop using aspirin 3 days prior to surgery.
d.	reduce the aspirin dosage by half until after surgery.

 

 

ANS:   B

Aspirin must be withdrawn at least 1 week prior to surgery.

Aspirin cannot be continued as scheduled, because the risk for bleeding is too great.

An interval of 3 days is not long enough for the bleeding effects of aspirin to be reversed.

Cutting the dose in half will not reduce the effects of bleeding associated with aspirin use.

 

DIF:    Cognitive Level: Application             REF:    p. 832

TOP:    Nursing Process: Implementation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies

 

4. The nurse is providing education to a patient who is to be discharged on a COX-2 inhibitor. The nurse would recognize that the patient understands the teaching if the patient states, “COX-2 inhibitors increase the risk of

a.	peptic ulcer disease.”
b.	liver toxicity.”
c.	acid-base imbalance.”
d.	myocardial infarction and stroke.”

 

 

ANS:   D

COX-2 inhibitors increase the risk of myocardial infarction and stroke.

The incidence of peptic ulcer disease is lower with COX-2 inhibitors than with COX-1 inhibitors.

In regular doses, COX-2 inhibitors are not toxic to the liver.

COX-2 inhibitors in regular doses do not affect acid-base balance.

 

DIF:    Cognitive Level: Application             REF:    p. 835 | p. 837

TOP:    Nursing Process: Evaluation

MSC:   NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies