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Chapter 78: Insulin, Glucagon, and Diabetes Mellitus

Guyton And Hall Textbook of Medical Physiology -12e by John E. Hall

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Chapter 78: Insulin, Glucagon, and Diabetes Mellitus

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

  1. A patient has uncontrolled type I diabetes. Which of the following is likely to be present?

A.    Decreased plasma osmolality

  1. Increased plasma volume
  2. Increased plasma pH

D.    Increased release of glucose from the liver

  1. Decreased rate of lipolysis

 

ANS: D

 

  1. Which of the following are incorrectly paired?
  1. Glucagon: increased glycogenolysis in liver
  2. Insulin: increased gluconeogenesis in liver
  3. Epinephrine: increased glycogenolysis in liver
  4. Epinephrine: increased glycogenolysis in muscle
  5. Cortisol: decreased glucose uptake in muscle

 

ANS: B

 

  1. A 60-year-old man comes to the physician’s office complaining of recent onset of fatigue and the need to urinate several times each night. He is 6′ tall and weighs 300 lbs. His blood pressure is 140/90. Laboratory data reveal a fasting blood glucose concentration of 270 mg/dL. Urinalysis reveals high urine glucose but no ketones. What is the most likely cause of this man’s symptoms?
  1. Type 1 diabetes mellitus
  2. Type 2 diabetes mellitus
  3. Addison’s disease
  4. Cushing’s disease
  5. Diabetes insipidus

 

ANS: B

 

  1. Which of the following metabolic responses would be expected during the postprandial period, compared to the postabsorptive state?

Lipoprotein Lipase      Hormone-Sensitive Lipase     Glycogen Phosphorylase

  1. ↑                                  ↑                                              ↓
  2. ↑                                  ↓                                              ↑
  3. ↑                                  ↓                                              ↓
  4. ↓                                  ↓                                              ↑
  5. ↓                                  ↑                                              ↑
  6. ↓                                  ↓                                              ↓

 

ANS: C

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