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Chapter 8: Adaptive Immunity

Pathophysiology The Biologic Basis for Disease in Adults and Children, 7th Edition by Kathryn L.

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Chapter 8: Adaptive Immunity

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

  1. Which primary characteristic is unique for the immune response?
a. The immune response is similar each time it is activated.
b. The immune response is specific to the antigen that initiates it.
c. The response to a specific pathogen is short term.
d. The response is innate, rather than acquired.

 

 

ANS:  B

Unlike inflammation, which is nonspecifically activated by cellular damage and pathogenic microorganisms, the immune response is primarily designed to afford long-term specific protection (i.e., immunity) against particular invading microorganisms; that is, it has a memory function. The other options are not unique characteristics of the immune response.

 

PTS:   1                    REF:   Page 225

 

  1. In which structure does B lymphocytes mature and undergo changes that commit them to becoming B cells?
a. Thymus gland c. Bone marrow
b. Regional lymph nodes d. Spleen

 

 

ANS:  C

B lymphocytes mature and become B cells in specialized (primary) lymphoid organs—the thymus gland for T cells and the bone marrow for B cells. Neither regional lymph nodes nor the spleen are involved in changing B lymphocytes into B cells.

 

PTS:   1                    REF:   Page 225

 

  1. What is the term for the process during which lymphoid stem cells migrate and change into either immunocompetent T cells or immunocompetent B cells?
a. Clonal diversity c. Clonal selection
b. Clonal differentiation d. Clonal competence

 

 

ANS:  A

The process is called the generation of clonal diversity and occurs in specialized (primary) lymphoid organs—the thymus gland for T cells and the bone marrow for B cells. The other options do not accurately identify the process described in the question.

 

PTS:   1                    REF:   Page 225

 

  1. Which type of immunity is produced by an individual after either natural exposure to the antigen or after immunization against the antigen?
a. Passive-acquired immunity c. Passive-innate immunity
b. Active-acquired immunity d. Active-innate immunity

 

 

ANS:  B

An individual produces active-acquired immunity (active immunity) after natural exposure to an antigen or after immunization, whereas passive-acquired immunity (passive immunity) does not involve the host’s immune response at all. The innate immune system, also known as nonspecific immune system and the first line of defense, is composed of the cells and mechanisms that defend the host from infection by other organisms in a nonspecific manner, which means that the cells of the innate system recognize and respond to pathogens in a generic way.

 

PTS:   1                    REF:   Page 227

 

  1. What type of immunity is produced when an immunoglobulin crosses the placenta?
a. Passive-acquired immunity c. Passive-innate immunity
b. Active-acquired immunity d. Active-innate immunity

 

 

ANS:  A

Passive-acquired immunity (passive immunity) does not involve the host’s immune response at all. Rather, passive immunity occurs when preformed antibodies or T lymphocytes are transferred from a donor to the recipient. This transfer can occur naturally, as in the passage of maternal antibodies across the placenta to the fetus, or artificially, as in a clinic using immunotherapy for a specific disease. The remaining options do not produce immunity via immunoglobulin transfer across the placenta.

 

PTS:   1                    REF:   Page 227

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