Chapter 8: Neuropathic Pain, Pain Matrix Dysfunction, and Pain Syndromes

Chapter 8: Neuropathic Pain, Pain Matrix Dysfunction, and Pain Syndromes

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

1. Which of the following characterize the late stage of complex regional pain syndrome?
2. Trauma
3. Red skin, excessive sweating, edema, skin atrophy
4. Lack of any sympathetic activity
5. Muscle atrophy, osteoporosis, arthritic changes
6. Excessive acetylcholine release by postganglionic neurons

ANS: D

Rationale: Trauma occurs prior to the development of CRPS. Skin changes and edema usually occur early in the disease process. Sympathetic nervous system activity is normal, as is acetylcholine release. Late stage CRPS is characterized by muscle atrophy, osteoporosis, and arthritic changes.

2. Tinel’s sign is associated with which of the following?
3. Avulsion of dorsal roots as a result of trauma
4. Maladaptive structural reorganization with phantom pain
5. Neuropathic syndrome associated with fibromyalgia
6. Ectopic foci associated with peripheral neuropathy
7. All of the above

ANS: D

Rationale: Tinel’s sign is pain or tingling elicited by tapping on an injured nerve. Tinel’s sign can only be elicited in the periphery, where neurons are not protected by the skull or vertebrae.

3. Migraine symptoms are thought to be related to amplification of nociceptive signals in which pathway?
4. Cranial nerve (CN) VII relay to spinal nucleus of thalamus
5. Spinothalamic pathway
6. Trigeminothalamocortical pathway
7. Fasciculus cuneatus relay to medial lemniscus
8. None of the above

ANS: C

Rationale: In migraine, function of the facial nerve (Cranial nerve VII), spinothalamic, and fasciculus cuneatus are normal. Activity in the trigeminothalamocortical pathway is amplified.

4. Which of the following contribute to chronic low back pain syndrome?
5. Muscle guarding
6. Abnormal movement
7. Disuse syndrome
8. A and B
9. A, B, and C

ANS: E

Rationale: Muscle guarding, abnormal movement, and disuse syndrome all contribute to chronic low back pain syndrome.