Chapter 8: Urine Screening for Metabolic Disorders

Chapter 8: Urine Screening for Metabolic Disorders

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

Multiple Choice

 

 

 

1. Phenylketonuria is caused by:
2. Excessive ingestion of milk products containing phenylalanine
3. Inability to metabolize tyrosine
4. Lack of the enzyme phenylalanine hydroxylase
5. A mousy odor in the urine

 

ANS: C

DIF: Level 1

OBJ: 3

TOP: Phenylketonuria

 

 

 

 

2. In patients with alkaptonuria, the abnormal metabolite that is present in the urine is:
3. Homogentisic acid
4. Alkaptonpyruvate
5. Phenylpyruvate
6. Tyrosine

 

ANS: A

DIF: Level 1

OBJ: 5

TOP: Alkaptonuria

 

 

 

3. Accumulation of large amounts of homogentisic acid in the urine is the result of which of the following disorders?
4. Alkaptonuria
5. Tyrosyluria
6. PKU
7. Homocystinuria

 

ANS: A

DIF: Level 1

OBJ: 5

TOP: Alkaptonuria

 

 

 

4. All of the following disorders are caused by defects in the phenylalanine-tyrosine pathway except:
5. Alkaptonuria
6. Hartnup disease
7. Tyrosyluria
8. PKU

 

ANS: B

DIF: Level 1

OBJ: 3

TOP: Phenylalanine-tyrosine disorders

 

 

 

5. Initial screening for PKU performed on newborns before their discharge from the hospital uses a blood sample rather than a urine sample because:
6. Urine samples are more difficult to collect
7. Serum bilirubin levels are routinely measured on all newborns
8. It is easier to measure phenylalanine than phenylpyruvic acid
9. Increased serum phenylalanine can be detected earlier

 

ANS: D

DIF: Level 1

OBJ: 3

TOP: Phenylketonuria