Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
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Chapter 89: Antimycobacterial Agents: Drugs for Tuberculosis, Leprosy, and
Mycobacterium avium Complex Infection
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| a. | Peripheral neuropathy |
| b. | Myopathy |
| c. | Crystalluria |
| d. | Red-orange-tinged urine |
ANS: D
Red-orange-tinged urine is a normal finding associated with rifampin.
Peripheral neuropathy, myopathy, and crystalluria are manifestations of adverse effects.
DIF: Cognitive Level: Application REF: p. 1044
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | “When a case is severe enough, multiple drugs are required.” |
| b. | “The more agents used, the shorter the duration of the therapy.” |
| c. | “Multiple agents prevent the emergence of resistant organisms.” |
| d. | “It is assumed that patients take about 50% of the prescribed drug.” |
ANS: C
The nurse’s best response would be that multiple agents prevent the emergence of resistant organisms.
Nothing indicates that the TB is severe.
The use of multiple agents does not shorten the duration of therapy.
It is not assumed that patients take about 50% of their medication.
DIF: Cognitive Level: Application REF: pp. 1038-1039
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | “The course of therapy generally lasts 1 year. Four drugs are required during that period.” |
| b. | “Most patients require 4 full months of therapy, followed by 1 year of weekly tuberculin skin tests.” |
| c. | “The four-drug regimen should last for 4 weeks. If the radiograph is normal, the medications are discontinued.” |
| d. | “The entire course should take 6 months; the first 2 months with four drugs, and the last 4 months with two drugs.” |
ANS: D
The most accurate description for the course of therapy for a newly diagnosed patient is that the entire course should take 6 months; the first 2 months with 4 drugs, and the last 4 months with 2 drugs.
Therapy does not take a year or 4 full months.
Therapy takes longer than 4 weeks.
DIF: Cognitive Level: Application REF: pp. 1039-1040
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | “After the sputum is converted to negative for TB organisms, the therapy continues for 12 to 24 months.” |
| b. | “The entire course of therapy lasts 3 to 6 months or until the chest radiograph is normal.” |
| c. | “Therapy is indefinite, because there is no method of determining responsiveness.” |
| d. | “No therapy is completely effective in multidrug-resistant tuberculosis, so treatment is needed for several years.” |
ANS: A
Multidrug resistance is defined as resistance to at least isoniazid and rifampin. Treatment requires at least three drugs to which the organism is sensitive and should continue for 12 to 24 months after sputum conversion. Initial therapy may consist of five, six, or even seven drugs.
Three to 6 months is too short a drug regimen.
Therapy is long but not indefinite
Treatment is required for 1 to 2 years, not several years.
DIF: Cognitive Level: Application REF: pp. 1039-1040
TOP: Nursing Process: Assessment
MSC: NCLEX Client Needs Category: Physiological Integrity: Reduction of Risk Potential
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