Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
Pharmacology for Nursing Care, 7th Edition by Richard A. Lehne
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Chapter 98: Antiprotozoal Drugs II: Miscellaneous Agents
Complete Chapter Questions With Answers
Sample Questions Are Posted Below
| a. | Pentamidine (Pentam) |
| b. | Iodoquinol (Yodoxin) |
| c. | Atovaquone (Mepron) |
| d. | Nitazoxanide (Alinia) |
ANS: B
The metronidazole concentration in the stomach remains low, therefore some amoebas survive. Using iodoquinol as the subsequent drug achieves high concentrations, killing the remaining amoebas.
Pentamidine, atovaquone, and nitazoxanide are indicated for treatment of diseases other than amebiasis.
DIF: Cognitive Level: Application REF: p. 1159
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity: Pharmacological and Parenteral Therapies
| a. | “I may experience nausea, diarrhea, and headache.” |
| b. | “I should report numbness in my extremities.” |
| c. | “I may experience large amounts of dilute urine.” |
| d. | “I should expect the medication to cause sores appear in my mouth.” |
| e. | “I may experience a metallic taste in my mouth.” |
ANS: C, D
The patient should expect to have dark urine, not dilute (colorless) urine; further teaching is required. The medication does not cause sores to appear in the mouth.
The patient may indeed experience nausea, diarrhea, and headache; no further teaching is required.
Numbness in the extremities should be reported, because it may indicate neurologic effects; no further teaching is required.
A metallic taste in the mouth is an expected effect of metronidazole; no further teaching is required.
DIF: Cognitive Level: Analysis REF: p. 1160
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity; Pharmacological and Parenteral Therapies
| a. | Pentamidine isethionate aerosol (NebuPent), one treatment every 4 weeks |
| b. | Pentamidine (Pentam 300), PO daily for 2 weeks |
| c. | Pentamidine intravenous (IV) injection once a week for a month |
| d. | Pneumococcal pneumonia vaccine |
ANS: A
The nurse should expect that the patient will be treated with pentamidine isethionate aerosol, one 300 mg treatment every 4 weeks, because this is the regimen for prophylaxis of P. jiroveci pneumonia.
Pentam 300 is injectable; it is not given PO.
IV injection of pentamidine is given daily for 2 to 3 weeks.
A pneumococcal vaccine is contraindicated for an immunocompromised patient.
DIF: Cognitive Level: Analysis REF: p. 1161
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity; Pharmacological and Parenteral Therapies
| a. | Trendelenburg; hypertensive crisis |
| b. | side-lying; injection discomfort |
| c. | supine; hypotension |
| d. | sitting; dizziness |
ANS: C
The patient should be lying supine during administration of the pentamidine infusion to minimize dizziness and hypotension.
The Trendelenburg position is not appropriate, and nothing indicates that the patient has hypertensive crisis.
The side-lying position will not minimize injection discomfort.
The sitting position is not appropriate; the patient should be supine.
DIF: Cognitive Level: Analysis REF: p. 1161
TOP: Nursing Process: Implementation
MSC: NCLEX Client Needs Category: Physiological Integrity; Pharmacological and Parenteral Therapies
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