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Drugs Society And Human Behavior 17th Edition By Carl L. -Test Bank

Drugs Society And Human Behavior 17th Edition By Carl L. -Test Bank   Instant Download - Complete Test Bank With Answers     Sample Questions Are Posted Below   Drugs, Society, & Behavior, 17e (Hart) Chapter 5   The Actions of Drugs   1) Most of our drugs originally came either directly or indirectly from: A) …

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Drugs Society And Human Behavior 17th Edition By Carl L. -Test Bank

 

Instant Download – Complete Test Bank With Answers

 

 

Sample Questions Are Posted Below

 

Drugs, Society, & Behavior, 17e (Hart)

Chapter 5   The Actions of Drugs

 

1) Most of our drugs originally came either directly or indirectly from:

  1. A) South America.
  2. B) plants.
  3. C) petroleum.
  4. D) German chemists.

 

Answer:  B

Page Ref: 99

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2) The ________ of a drug specifies a particular formulation and manufacturer, and the trademark belongs to that manufacturer.

  1. A) preferred name
  2. B) generic name
  3. C) brand name
  4. D) international nonproprietary name

 

Answer:  C

Page Ref: 100

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3) The group of psychoactive drugs called stimulants includes:

  1. A) cocaine.
  2. B) Prozac.
  3. C) LSD.
  4. D) heroin.

 

Answer:  A

Page Ref: 101

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4) Among the psychoactive drugs, alcohol can be classified as a(n) ________.

  1. A) stimulant
  2. B) opioid
  3. C) hallucinogen
  4. D) depressant

 

Answer:  D

Page Ref: 101

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5) ________ are a group of analgesic (painkilling) drugs that produce a relaxed, dreamlike state; moderately high doses often induce sleep.

  1. A) Hallucinogens
  2. B) Opioids
  3. C) Antipsychotics
  4. D) Antidepressants

 

Answer:  B

Page Ref: 102

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6) Richard is a researcher in a pharmaceutical company. His company develops a new drug to treat chronic joint pain in humans. He wants to check the effect of this drug on a group of elderly people. He divides the group into an experimental group and a control group. He gives the new drug to the experimental group, while he gives a noneffective look-alike drug to the control group. Both groups give the same result. Identify the effect felt by the control group, despite not taking the drug.

  1. A) Specific effect
  2. B) Observer effect
  3. C) Nocebo effect
  4. D) Placebo effect

 

Answer:  D

Page Ref: 103

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7) The effects of a drug that depend on the presence of a chemical at certain concentrations in a target tissue are called ________.

  1. A) placebo effects
  2. B) observer effects
  3. C) specific effects
  4. D) nocebo effects

 

Answer:  C

Page Ref: 103

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8) When neither the person taking the drug nor the person evaluating the effects of the drug knows which people are getting the experimental drug and which people are getting the placebo, this procedure is referred to as a(n) ________.

  1. A) design flaw
  2. B) effect size
  3. C) preclinical study
  4. D) double-blind procedure

 

Answer:  D

Page Ref: 103

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9) The threshold on a dose-response curve is the:

  1. A) point at which the dose of a drug causes maximal response.
  2. B) lowest dose at which there is an observable effect of a drug.
  3. C) safe effective dose of a drug.
  4. D) therapeutic index of a drug.

 

Answer:  B

Page Ref: 104

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10) Which of the following terms is defined as the dosage difference between an acceptable level of effectiveness and the lowest toxic dose?

  1. A) Safety margin
  2. B) Therapeutic index
  3. C) Drug potency
  4. D) Cumulative effect

 

Answer:  A

Page Ref: 106

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11) With increasing doses of any useful drug, there is usually an increase in the number and severity of:

  1. A) side effects.
  2. B) beneficial effects.
  3. C) placebo effects.
  4. D) effects on the stomach.

 

Answer:  A

Page Ref: 106

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12) The potency of a drug is defined in terms of:

  1. A) the magnitude of the effect it produces.
  2. B) its dependence potential.
  3. C) whether it has a detectable odor.
  4. D) the amount required to produce an effect.

 

Answer:  D

Page Ref: 106

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13) Which of the following statements is true of the potency of a drug?

  1. A) The smaller the amount needed to get a particular effect, the more potent the drug.
  2. B) Potency strongly relates to how effective a drug is or to how large an effect the drug can produce.
  3. C) Potency refers to the relative lethal dose of a drug, especially the cannabinoids and the opioids.
  4. D) The ED50(the effective dose for 50 percent of the animals) of a potent drug is higher than the ED50of a less potent drug.

 

Answer:  A

Page Ref: 106

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14) Which of the following would be a reason for a drug company not to pursue expensive clinical trails with a new drug?

  1. A) The drug produces no side effects.
  2. B) The drug produces side effects.
  3. C) The therapeutic index is greater than 1.
  4. D) The therapeutic index is less than 1.

 

Answer:  D

Page Ref: 106

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15) The time course of a drug’s action depends on:

  1. A) how the drug is administered.
  2. B) how rapidly the drug is absorbed.
  3. C) how the drug is eliminated from the body.
  4. D) all of these answers are correct.

 

Answer:  D

Page Ref: 107

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16) Regardless of the route of administration, psychoactive drugs reach the brain tissue by way of the ________.

  1. A) meninges
  2. B) spinal cord
  3. C) bloodstream
  4. D) liver

 

Answer:  C

Page Ref: 109

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17) After oral administration, most absorption of the drug molecules takes place in the:

  1. A) small intestine.
  2. B) kidneys.
  3. C) heart.
  4. D) lower bowel.

 

Answer:  A

Page Ref: 110

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18) If you want to get very high concentrations of cocaine to the brain very rapidly, which route of administration would you probably use?

  1. A) Oral administration
  2. B) Subcutaneous injection
  3. C) Topical application
  4. D) Intravenous injection

 

Answer:  D

Page Ref: 112

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19) Of the following routes of administration, which will produce fastest onset of effects?

  1. A) Inhalation
  2. B) Intramuscular injection
  3. C) Using a rectal suppository
  4. D) Rubbing it on the head

 

Answer:  A

Page Ref: 113

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20) Alcohol has a low tendency, but THC has a high tendency, to:

  1. A) bind to the serotonin receptor.
  2. B) dissolve in water.
  3. C) bind to blood proteins.
  4. D) produce dependence.

 

Answer:  C

Page Ref: 114

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21) The blood-brain barrier:

  1. A) is fully developed in humans when they are born.
  2. B) is designed to allow all drug compounds into the brain.
  3. C) cannot be penetrated, even with trauma to the brain.
  4. D) prevents many drugs from entering the brain.

 

Answer:  D

Page Ref: 114

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22) Concussions and cerebral infections can decrease the effectiveness of:

  1. A) drug metabolism.
  2. B) the blood-brain barrier.
  3. C) protein binding.
  4. D) multiple drug doses.

 

Answer:  B

Page Ref: 115

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23) Some drugs may act on all types of neurons by:

  1. A) blocking all receptor types.
  2. B) interfering with metabolism.
  3. C) preventing absorption of nutrients.
  4. D) altering the electrical potential across the cell membrane.

 

Answer:  D

Page Ref: 115

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24) The most common way for drug molecules to be deactivated is by:

  1. A) the action of CYP450 enzymes in the liver.
  2. B) protein binding.
  3. C) elimination through the bowel.
  4. D) reuptake.

 

Answer:  A

Page Ref: 116

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25) If repeated exposure to a drug increases the activity of the CYP450 enzyme that is responsible for metabolizing that drug, then later doses will be less effective than the first few doses. This is an example of:

  1. A) drug disposition tolerance.
  2. B) behavioral tolerance.
  3. C) an active metabolite.
  4. D) a prodrug.

 

Answer:  A

Page Ref: 117

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26) ________ are defined as the drugs that are inactive until acted on by enzymes in the body.

  1. A) Prodrugs
  2. B) Codrugs
  3. C) Active metabolites
  4. D) Channel openers

 

Answer:  A

Page Ref: 117

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27) When the use of a drug interferes with normal behavior, experienced users may learn to compensate and show less impairment than new users. This is an example of:

  1. A) drug disposition tolerance.
  2. B) behavioral tolerance.
  3. C) an active metabolite.
  4. D) a prodrug.

 

Answer:  B

Page Ref: 118

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28) A drug’s generic name can only be used by one company.

 

Answer:  FALSE

Page Ref: 100

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29) Caffeine and cocaine are both considered to be stimulant drugs.

 

Answer:  TRUE

Page Ref: 101

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30) The therapeutic index (TI) should always be lesser than 1 because the lethal dose should be larger than the effective dose.

 

Answer:  FALSE

Page Ref: 106

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31) For most therapeutic effects, there is a maximum effect, and increasing the dose more just increases the number and severity of side effects.

 

Answer:  TRUE

Page Ref: 106

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32) According to the text, inexperienced drug users should avoid taking a drug via a route that increases the drug’s potency.

 

Answer:  TRUE

Page Ref: 107

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33) Most psychoactive drugs taken orally go directly from the stomach to the brain.

 

Answer:  FALSE

Page Ref: 110

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34) For many psychoactive drugs, such as nicotine and cocaine, the fastest way to get an effect is by inhaling the drug’s vapors.

 

Answer:  TRUE

Page Ref: 113

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35) Because the effects of stimulants and depressants counteract each other, taking these drugs in combination does not produce intoxication.

 

Answer:  FALSE

Page Ref: 116

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36) What is the placebo effect? Describe some research techniques that have been developed to separate specific drug effects from placebo effects.

 

Answer:  The placebo effect is an effect that does not depend on the presence of a specific chemical in the system. Double-blind procedures and dose-response curves are two ways of demonstrating specific drug effects.

Page Ref: 103-104

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37) Explain why an experienced heroin user would most likely choose to smoke or inject the drug rather than taking it orally. Then explain why inexperienced users should initially be discouraged from these routes of administration.

 

Answer:  An experienced heroin user will smoke or inject the drug because these routes produce a more intense high (because of a fast rate of onset) and less of the drug will be needed (because none will be metabolized by the stomach and/or liver). These routes are less safe for the inexperienced user because they have not built tolerance, and thus, small drug doses with a fast onset are more likely to produce toxic effects.

Page Ref: 107

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38) Describe three factors that can influence the time course of the behavioral effect of a drug, and show that you understand how each factor influences the time course.

 

Answer:  1) Route of administration, 2) speed of absorption (both influence how fast the drug acts and how long it takes to reach its maximum effect), and 3) how the drug is eliminated (mainly influences how long it lasts). Other possible answers include protein binding, drug distribution (e.g., fat storage). Bonus: discussion of metabolism by CYP450 enzymes in the liver, drug disposition tolerance.

Page Ref: 109-117

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39) There are many different routes by which drugs can be administered. Describe the pros and cons of the oral route versus the intravenous route.

 

Answer:  Oral administration: pros are that it is simpler and relatively safer technique; cons are that absorption from gastrointestinal tract is slow and complicated by many factors.

Intravenous administration: pros include short onset of action, ability to deliver irritating material because the blood vessel walls are relatively insensitive; cons are that vein walls lose some elasticity over time and can eventually collapse, can introduce infection directly into bloodstream.

Page Ref: 110-113

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40) Describe three mechanisms that might explain why an alcohol-dependent individual might have to take more of the drug to experience the same effects.

 

Answer:  The three mechanisms are 1) drug disposition tolerance—use of a drug that increases a drug’s rate of metabolism or excretion, therefore requiring a greater dose to obtain the same result; 2) behavioral tolerance—individuals learn to adapt to the altered state and compensate for the impairment; and 3) pharmacodynamic tolerance—sensitivity of neurons to drug changes in an attempt by the brain to maintain its level of functioning within normal limits.

Page Ref: 117-118

Bloom’s:  Understand

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