Genetics Analysis and Principles 5th Edition by Brooker - Test Bank

Genetics Analysis and Principles 5th Edition by Brooker – Test Bank

 

Instant Download – Complete Test Bank With Answers

 

 

Sample Questions Are Posted Below

 

Chapter 05

Non-Mendelian Inheritance

 

 

Multiple Choice Questions

1. Which of the following is primarily responsible for the maternal effect?
   A.Sperm cells
   B. Oocytes
   C. Nurse cells
   D. Placenta

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.01.01 Define maternal effect.
Learning Outcome: 05.01.03 Explain the molecular mechanism of maternal effect.
Section: 05.01
Topic: Maternal Effect

2. In the gene that affects snail coiling, the ______ is responsible for the phenotype of the offspring.
   A. mother’s phenotype
   B.  father’s phenotype
   C.  mother’s genotype
   D.  father’s genotype

 

Accessibility: Keyboard Navigation
Bloom’s Level: 3. Apply
Learning Outcome: 05.01.02 Predict the outcome of crosses for genes that exhibit a maternal effect pattern of inheritance.
Learning Outcome: 05.01.03 Explain the molecular mechanism of maternal effect.
Section: 05.01
Topic: Maternal Effect

 

3. Which of the following does not inactivate an X chromosome?
   A.Mammals
   B. Drosophila
   C. C. elegans
   D. Marsupials

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

4. Who originally identified a highly condensed structure in the interphase of nuclei?
   A.Lyon
   B. Barr
   C. Ohno
   D. None of the answers are correct

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Learning Outcome: 05.02.04 Explain how X-chromosome inactivation may affect the phenotype of female mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

5. What gene is encoded in the Xic?
   A.Xce
   B. Xist
   C. Tsix
   D. None of these

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

 

6. What genes appear to be controlled by the Xic?
   A.Xist and Tsix
   B. Xist only
   C. Tsix only
   D. None of these

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

7. Expression of ______ would inhibit X-inactivation.
   A.Xic
   B. Xist
   C. Tsix
   D. All of the answers are correct
   E. None of the answers are correct

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

8. What gene is most responsible for X-inactivation?
   A.Xic
   B. Xist
   C. Tsix
   D. Xce

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

 

True / False Questions
 

9. Both parents usually imprint the same gene.
   FALSE

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

 

Multiple Choice Questions

10. In the Igf2 gene, which allele is imprinted? Which is expressed?
    A.Paternal, paternal
    B. Paternal, maternal
    C. Maternal, paternal
    D. Maternal, maternal

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.02 Predict the outcome of crosses involving imprinted genes.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

11. What is the molecular mechanism for imprinting a gene?
    A.Acetylation
    B. Nitration
    C. Phosphorylation
    D. Methylation

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

 

12. Most imprinted genes are silenced. What is one exception to this rule?
    A.H19
    B. Igf2
    C. UBE3A
    D. SNRPN

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.01 Define epigenetic inheritance.
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.02 Predict the outcome of crosses involving imprinted genes.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.02
Section: 05.03
Topic: Epigenetic Inheritance: Dosage Compensation
Topic: Epigenetic Inheritance: Genomic Imprinting

13. Which diseases are associated with imprinting?
    A.Angelman Syndrome
    B. LHON
    C. Alzheimer’s Disease
    D. All of the answers are correct

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.02.01 Define epigenetic inheritance.
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.02 Predict the outcome of crosses involving imprinted genes.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.02
Section: 05.03
Topic: Epigenetic Inheritance: Dosage Compensation
Topic: Epigenetic Inheritance: Genomic Imprinting

 

In which cells do erasure and re-establishment of imprinting marks typically NOT occur?

1. Nurse cells
   B. Sperm cells
   C. Oocytes
   D. Somatic cells

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.01 Define epigenetic inheritance.
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.02 Predict the outcome of crosses involving imprinted genes.
Section: 05.02
Section: 05.03
Topic: Epigenetic Inheritance: Dosage Compensation
Topic: Epigenetic Inheritance: Genomic Imprinting

15. Where is extranuclear DNA located in mammalian cells?
    A.Endoplasmic reticulum
    B. Mitochondria
    C. Ribosome
    D. Plasma membrane

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Section: 05.04
Topic: Extranuclear Inheritance

 

16. What type of inheritance is observed with extranuclear DNA?
    A.Mendelian inheritance
    B. Sex-linked inheritance
    C. Paternal inheritance
    D.

Maternal inheritance

Maternal effect

 

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Section: 05.04
Topic: Extranuclear Inheritance

17. What is a disease associated with extra nuclear inheritance?
    A.Angelman Syndrome
    B. Prader-Willi Syndrome
    C. LHON
    D. Muscular Dystrophy

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.03 Explain how mutations in mitochondrial genes cause human diseases.
Section: 05.04
Topic: Extranuclear Inheritance

 

18. What is thought to be the origin of mitochondria and chloroplasts?
    A.Cyanobacteria for mitochondria, purple bacteria for chloroplasts
    B. Purple bacteria for mitochondria, fungi for chloroplasts
    C. Purple bacteria for mitochondria, cyanobacteria for chloroplasts
    D. Algae for mitochondria, cyanobacteria for chloroplasts

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.04 Evaluate the endosymbiosis theory.
Section: 05.04
Topic: Extranuclear Inheritance

19. What encodes the toxin paramecin in Paramecia aurelia?
    A.mtDNA
    B. cpDNA
    C. Nuclear DNA
    D. Kappa particles

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

20. Who is largely responsible for proposing the endosymbiosis theory?
    A.Schimper, Wallin, Margulis
    B. Lyon, Margulis, Schimper
    C. Schimper, Wallin, Barr
    D. Barr, Lyon, Margulis

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.04 Evaluate the endosymbiosis theory.
Section: 05.04
Topic: Extranuclear Inheritance

 

Which inheritance pattern is common to oogenesis, spermatogenesis, and embryogenesis?

Maternal inheritance

Epigenetic inheritance

Maternal effect

Paternal inheritance

 

 

Accessibility: Keyboard Navigation
Bloom’s Level: 3. Apply
Learning Outcome: 05.02.01 Define epigenetic inheritance.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

22. How many Barr bodies would an individual with a XXY genotype possess?
    A.0
    B. 1
    C. 2
    D. None of the answers are correct

 

Accessibility: Keyboard Navigation
Bloom’s Level: 3. Apply
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Learning Outcome: 05.02.04 Explain how X-chromosome inactivation may affect the phenotype of female mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

 

23. The coat color of calico cats is a result of _____.
    A. maternal inheritance
    B.  X-inactivation
    C.  imprinting
    D.  extranuclear inheritance

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Learning Outcome: 05.02.04 Explain how X-chromosome inactivation may affect the phenotype of female mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

24. The Lyon hypothesis attempts to explain the molecular mechanism of _____.
    A. X-inactivation
    B.  genomic imprinting
    C.  maternal inheritance
    D.  extranuclear inheritance

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.02.02 Compare and contrast how dosage compensation is achieved in different animal species.
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Learning Outcome: 05.02.04 Explain how X-chromosome inactivation may affect the phenotype of female mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

25. Monoallelic expression is associated with which of the following?
    A.X-inactivation
    B. Genomic imprinting
    C. Maternal inheritance
    D. Extranuclear inheritance

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

 

26. Differentially methylated domains (DMDs) are associated with which of the following?
    A.X-inactivation
    B. Genomic imprinting
    C. Maternal inheritance
    D. Extranuclear inheritance
    E. All of the answers are correct

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.03.01 Define genomic imprinting.
Learning Outcome: 05.03.03 Explain the molecular mechanism of imprinting.
Section: 05.03
Topic: Epigenetic Inheritance: Genomic Imprinting

27. Which of the following is false regarding mtDNA?
    A. It is around 17,000 bp in length
    B.  It is a linear chromosome
    C.  Multiple copies exist in each mitochondria
    D.  It mostly contains rRNA and tRNA genes

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Learning Outcome: 05.04.03 Explain how mutations in mitochondrial genes cause human diseases.
Section: 05.04
Topic: Extranuclear Inheritance

 

True / False Questions

28. mtDNA contains all of the genes necessary for the complete function of mitochondrial metabolism.
    FALSE

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Learning Outcome: 05.04.03 Explain how mutations in mitochondrial genes cause human diseases.
Section: 05.04
Topic: Extranuclear Inheritance

 

 

 

Multiple Choice Questions

29. Which of the following categories of genes is typically NOT encoded in cpDNA?
    A. Genes encoding rRNA
    B.  Genes encoding tRNA
    C.  Genes for photosynthetic pathway enzymes
    D.  Genes encoding nuclear proteins

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Section: 05.04
Topic: Extranuclear Inheritance

30. The inheritance of leaf pigmentation in the four-o’clock plant Mirabilis jalapa is an example of ____.
    A. maternal effect
    B.  maternal inheritance
    C.  epigenetic inheritance
    D.  imprinting

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.02 Predict the outcome of crosses involving extranuclear inheritance.
Section: 05.04
Topic: Extranuclear Inheritance

31. Chlamydomonas was used as the model organism for the study of _____.
    A. chloroplast inheritance
    B.  mitochondrial inheritance
    C.  genomic imprinting
    D.  methylation of DNA

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Learning Outcome: 05.04.04 Evaluate the endosymbiosis theory.
Section: 05.04
Topic: Extranuclear Inheritance

 

32. In maternal effect, the _______ of the mother determines the _______ of the offspring.
    A.phenotype, genotype
    B. genotype, phenotype
    C. rRNA, tRNA
    D. imprinting, genotype

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.01.01 Define maternal effect.
Learning Outcome: 05.01.02 Predict the outcome of crosses for genes that exhibit a maternal effect pattern of inheritance.
Learning Outcome: 05.01.03 Explain the molecular mechanism of maternal effect.
Section: 05.01
Topic: Maternal Effect

33. A modification that occurs to a nuclear gene that alters gene expression without modifying the DNA sequence is called _______ inheritance.
    A.extranuclear
    B. cytoplasmic
    C. maternal effect
    D. epigenetic
    E. nuclear

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.02.01 Define epigenetic inheritance.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

34. Dosage compensation offsets the problems associated with differences in the number of _______ chromosomes in many species.
    A. cytoplasmic
    B.  autosome
    C.  sex
    D.  extranuclear
    E.  mitochondrial

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.02.03 Describe the process of X-chromosome inactivation in mammals.
Learning Outcome: 05.02.04 Explain how X-chromosome inactivation may affect the phenotype of female mammals.
Section: 05.02
Topic: Epigenetic Inheritance: Dosage Compensation

 

35. The inheritance patterns of genetic material that is not contained in the nucleus of the cell is called _______.
    A.extranuclear inheritance
    B. maternal effect
    C. imprinting
    D. nuclear
    E. epigenetic

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Section: 05.04
Topic: Extranuclear Inheritance

36. mtDNA stands for _______ and cpDNA stands for _______.
    A. extranuclear DNA, cytoplasmic DNA
    B.  maternal DNA, paternal DNA
    C.  marked DNA, copied DNA
    D.  nuclear, cytoplasmic
    E.  mitochondrial DNA, chloroplast DNA

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.01 Describe the general features of the mitochondrial and chloroplast genomes.
Section: 05.04
Topic: Extranuclear Inheritance

37. Heteroplasmy is associated with inheritance patterns involving
    A. nuclear.
    B.  paternal DNA.
    C.  chloroplasts.
    D.  ribosomes.
    E.  imprinted.

 

Accessibility: Keyboard Navigation
Bloom’s Level: 2. Understand
Learning Outcome: 05.04.03 Explain how mutations in mitochondrial genes cause human diseases.
Section: 05.04
Topic: Extranuclear Inheritance

 

38. If the sperm cell contributes mitochondria to the oocyte, it is called _______.
    A. paternal leakage
    B.  maternal leakage
    C.  paternal inheritance
    D.  mitochondria
    E.  imprinting

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.03 Explain how mutations in mitochondrial genes cause human diseases.
Section: 05.04
Topic: Extranuclear Inheritance

39. A symbiotic relationship where one organism lives inside another species is called _______.
    A.cytoplasmic inheritance
    B. heteroplasmy
    C. paternal leakage
    D. endosymbiosis

 

Accessibility: Keyboard Navigation
Bloom’s Level: 1. Remember
Learning Outcome: 05.04.04 Evaluate the endosymbiosis theory.
Section: 05.04
Topic: Extranuclear Inheritance