Human Heredity Principles and Issues 10th Edition by Michael Cummings - Test Bank
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Human Heredity Principles and Issues 10th Edition by Michael Cummings - Test Bank

Human Heredity Principles and Issues 10th Edition by Michael Cummings - Test Bank   Instant Download - Complete Test Bank With Answers     Sample Questions Are Posted Below   6. Y-linked traits areA. known as hemizygous traits.B. known to skip alternate generations of males.C. carried only by males and transmitted only to males.D. known …

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Human Heredity Principles and Issues 10th Edition by Michael Cummings – Test Bank

 

Instant Download – Complete Test Bank With Answers

 

 

Sample Questions Are Posted Below

 

6. Y-linked traits are
A. known as hemizygous traits.
B. known to skip alternate generations of males.
C. carried only by males and transmitted only to males.
D. known to skip alternate generations of males and are carried only by males and transmitted
only to males.
E. known as hemizygous traits and are carried only by males and transmitted only to males.
ANS: E PTS: 1
7. Hemophilia was a significant issue in the life of
A. Abraham Lincoln.
B. Olympic volleyball star Flo Hyman.
C. Noah.
D. the family of the last tsar of Russia.
E. King George III of England.
ANS: D PTS: 1
8. A child is born with a lethal dominant allele. This would seem to be impossible since either parent, had
they possessed this allele, would have suffered its lethal effects. What is a possible explanation?
A. The child’s allele is a spontaneous mutation that neither parent had to deal with.
B. The allele could have varying expressivity and not always be lethal.
C. The allele could have delayed onset.
D. All of these are possible.
E. None of these is possible.
ANS: D PTS: 1
9. Two phenotypically normal parents have six children. Two daughters and two sons have the same genetic
disease. This would be the expected situation for
A. hemophilia.
B. cystic fibrosis.
C. Marfan syndrome.
D. hypophosphatemia.
E. all of these.
ANS: B PTS: 1
10. Which one of the following is NOT usually a symptom of cystic fibrosis?
A. Low fertility or infertility
B. Frequent respiratory infections
C. Difficulty breathing
D. Loss of pancreatic function
E. Problems with hearing and vision
ANS: E PTS: 1
11. Dystrophin is a protein that normally
A. shortens and lengthens to produce muscle contraction.
B. carries signals into muscle cells to initiate contraction.
C. strengthens the attachment between muscle proteins and the plasma membrane.
D. helps provide energy for muscle contraction.Human Heredity Principles and Issues 10th Cummings
E. signals muscle cells to divide.
ANS: C PTS: 1
12. Camptodactyly
A. causes bent, immobile little fingers.
B. is inherited as a dominant trait.
C. shows less than complete penetrance.
D. shows varying expressivity.
E. is characterized by all of these.
ANS: E PTS: 1
13. Approximately how many Y-linked genes have been discovered?
A. None D. 100
B. 10 E. 300
C. 36
ANS: C PTS: 1
14. Which of the following is NOT a symptom of Marfan syndrome?
A. Vision problems
B. Blood vessel defects
C. Loose joints
D. Short stature
E. All of these are symptoms of Marfan syndrome
ANS: D PTS: 1
15. The gene responsible for Marfan syndrome encodes a protein associated with
A. heart muscle. D. red blood cells.
B. connective tissue. E. nervous tissues.
C. fat tissue.
ANS: B PTS: 1
16. Which of the following is a goal of pedigree analysis?
A. To determine dominance and recessive patterns.
B. To determine if a gene is sex-linked or autosomal.
C. To determine gene loci.
D. To determine dominance and recessive patterns and if a gene is sex-linked or autosomal.
E. To determine gene loci and if a gene is sex-linked or autosomal.
ANS: D PTS: 1
17. If a pedigree of several generations shows only females affected by a particular trait, what can be ruled
out?
A. Autosomal recessive inheritance D. X-linked recessive inheritance
B. X-linked dominant inheritance E. None of these can be ruled out
C. Y-linked inheritance
ANS: C PTS: 1Human Heredity Principles and Issues 10th Cummings
18. Which of the following is NOT a characteristic of an autosomal recessive trait?
A. All of the children of two affected
individuals are affected.
D. Every affected individual has at least one
affected parent.
B. If two individuals are heterozygous, the
risk of having an affected child is 1:4.
E. All of these are characteristic of an
autosomal recessive trait.
C. For rare traits, affected individuals have
unaffected parents.
ANS: D PTS: 1
19. Amal has a serious metabolic disorder known as PKU. His sister has the same disorder. Neither of Amal’s
parents have the disorder. What is the most likely inheritance pattern of this disorder?
A. Autosomal dominant
B. Autosomal recessive
C. X-linked dominant
D. X-linked recessive
E. It is not possible to tell the inheritance pattern from this information.
ANS: B PTS: 1
20. The main problem for sufferers of cystic fibrosis is
A. abnormal hemoglobin. D. missing DNA repair enzymes.
B. elevated levels of cholesterol. E. formation of cysts in kidneys.
C. mucus blocking ducts of glands.
ANS: C PTS: 1
21. The underlying problem with cystic fibrosis is
A. the inability to transport chloride ions.
B. mutations in the hemoglobin molecule.
C. defective ganglioside molecules.
D. the inability to metabolize certain amino acids.
E. abnormal fat deposits around the heart.
ANS: A PTS: 1
22. What are the chances that a woman who is color blind will have a son who is color blind?
A. 0 percent D. 75 percent
B. 25 percent E. 100 percent
C. 50 percent
ANS: E PTS: 1
23. Valeria has a serious disorder called fragile X syndrome and her brother does not have the disorder. Her
mother does not have the disorder but her father does. What is the most likely inheritance pattern for
fragile X syndrome?
A. Autosomal dominant D. X-linked recessive
B. Autosomal recessive E. Y-linked recessive
C. X-linked dominant
ANS: C PTS: 1Human Heredity Principles and Issues 10th Cummings
TRUE/FALSE
1. Mendel’s laws apply to all sexually reproducing organisms. Therefore, the basic methods of genetic
analysis in humans and other organisms is the same.
ANS: F PTS: 1
2. Human traits are controlled only by the genetic material found in the 46 chromosomes.
ANS: F PTS: 1
3. The phenotypes of a trait controlled by the same gene are not always identical.
ANS: T PTS: 1
4. More than one mode of inheritance can be seen for a single trait.
ANS: T PTS: 1
5. The analysis of a pedigree is complete when the information in the pedigree supports the hypothesis
formed by the geneticist.
ANS: F PTS: 1
6. Autosomal dominant traits are inherited from affected parents.
ANS: T PTS: 1
7. The frequency of heterozygotes for cystic fibrosis shows ethnic variations.
ANS: T PTS: 1
8. Duchenne muscular dystrophy and Becker’s muscular dystrophy represent allelic forms of the same X-
linked gene.
ANS: T PTS: 1
9. All genes are expressed in either the prenatal or newborn stages.
ANS: F PTS: 1
10. Color blindness only occurs in males.
ANS: F PTS: 1
11. People with cystic fibrosis have difficulty digesting food properly.
ANS: T PTS: 1
12. Variation in expressivity and penetrance of genes is due to the effects of other genes and the environment.Human Heredity Principles and Issues 10th Cummings
ANS: T PTS: 1
COMPLETION
1. The basic method of genetic analysis in humans is ____________________ rather than experimental.
ANS: observational
PTS: 1
2. The basic method of genetic analysis in humans requires a ____________________ of several
generations.
ANS:
family history
pedigree
PTS: 1
3. A color-blind man has a son who is also color blind. The son inherited the condition from his
____________________.
ANS: mother
PTS: 1
4. If a man and his wife are both homozygous for a disease-causing recessive gene, then
____________________ of their children will be affected.
ANS: all
PTS: 1
5. Adults who have children who have died from lethal recessive disorders are most likely
____________________.
ANS: heterozygous
PTS: 1
6. If a man and his wife are affected with a dominant trait, then ____________________ of their children
could be unaffected.
ANS:
some
one fourth
PTS: 1
7. The degree to which a trait is expressed in individuals is the ____________________ of the trait.Human Heredity Principles and Issues 10th Cummings
ANS: expressivity
PTS: 1
8. The proportion of individuals in a population expressing a trait when they have the appropriate genotype
represents the percent of ____________________ for the trait.
ANS: penetrance
PTS: 1
9. A missing or ineffective chlorine ion transporter is the cause of ____________________.
ANS: cystic fibrosis
PTS: 1
10. The gene that codes for the connective tissue protein fibrillin is the gene that causes
____________________.
ANS: Marfan syndrome
PTS: 1
11. Huntington’s disease, a severe autosomal dominant neurological disorder, shows a
____________________ in its expression.
ANS: delayed onset
PTS: 1
12. Genetic diseases transmitted only by a mother to both sons and daughters result from
____________________ genes.
ANS: mitochondrial
PTS: 1
13. When affected males produce all affected daughters and no affected sons, the genetic disease is likely to
be ____________________.
ANS: X-linked dominant
PTS: 1
14. If Marfan syndrome results in death, it is usually due to rupture of the ____________________.
ANS: aorta
PTS: 1Human Heredity Principles and Issues 10th Cummings
15. The most common forms of color blindness cause inability to properly perceive the colors
____________________ and ____________________.
ANS: red; green
PTS: 1
16. Mitochondrial gene defects mainly cause myopathies (conditions affecting ____________________), and
encephalomyopathies (conditions also affecting ____________________).
ANS: muscles; the brain
PTS: 1
17. A defective form of the protein dystrophin is involved in the diseases __________ and ________.
ANS: Duchenne muscular dystrophy; Becker muscular dystrophy
PTS: 1
SHORT ANSWER
1. Compared to experimental organisms such as the garden pea, why is it that humans are poor subjects for
genetic investigations?
ANS:
Answer not provided.
PTS: 1
2. In pedigree analysis, is it always possible to determine the mode of inheritance for a trait? What factors
can complicate this task?
ANS:
Answer not provided.
PTS: 1
3. Is it easier to work out pedigrees for dominant traits than for recessive ones? What can complicate the
analysis of dominant traits?
ANS:
Answer not provided.
PTS: 1
4. How do each of the following affect the expression of single gene traits: incomplete dominance,
expressivity, penetrance?Human Heredity Principles and Issues 10th Cummings
ANS:
Answer not provided.
PTS: 1
5. Tomas has a rare genetic defect that causes him to snore excessively. Tomas’s partner, Glora, does not
have this problem. Tomas’s sister, Eloise, also does not have this problem. Eloise has a daughter who is
normal and identical twin boys who snore excessively like Tomas. The parents of Tomas, Eloise, and
Gloria are all normal. Draw a pedigree for this family. What is the mode of transmission of this defect?
ANS:
Answer not provided.
PTS: 1
6. Explain the inheritance of mitochondrial DNA and how a person inherits a mitochondrial genetic disease.
ANS:
Answer not provided.
PTS: 1
7. How would you distinguish between a trait that is X-linked dominant trait and one that is autosomal
dominant?
ANS:
Answer not provided.
PTS: 1
8. A large family exhibits a previously undiscovered trait: green hair. One parent has the trait as do 6 of their
12 children (50%). (a) Satisfy yourself that this result could be produced by either one of two situations:
Green hair is caused by a dominant allele, and the green-haired parent has one copy of that allele; OR
green hair is a recessive trait; the green-haired parent is homozygous and the other parent is heterozygous.
(b) How might we determine which one of these possibilities is true?
ANS:
Answer not provided.
PTS: 1

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