Chapter 23: Drug Therapy for Gastric Ulcers and Reflux

Understanding Pharmacology Essentials For Medication Safety By M. Linda Workman

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Chapter 23: Drug Therapy for Gastric Ulcers and Reflux

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

 

BASIC CONCEPTS

 

  1. Which bacteria is often the cause of stomach ulcers?
a. Escherichia coli
b. Helicobacter pylori
c. Staphylococcus aureus
d. Streptococcus pneumoniae

 

 

ANS:  B

Research has shown that 80% to 90% of gastric ulcers are caused by infection with the Helicobacter pylori (H. pylori) bacteria. H. pylori infection is present in 20% to 30% of people in the United States. Some people experience no signs or symptoms, whereas others develop ulcers.

 

DIF:    Cognitive Level: Remembering        REF:   p. 374

 

  1. Which problem indicates a gastric ulcer is getting worse?
a. Gaining weight
b. Abdominal gas
c. Frequent diarrhea
d. Blood in the stools

 

 

ANS:  D

A major sign that indicates an ulcer is getting worse is blood in stools. Other signs are listed in Box 23-2 in the text.

 

DIF:    Cognitive Level: Remembering        REF:   p. 376, Box 23-2

 

  1. What is the most common symptom of gastroesophageal reflux disease (GERD)?
a. Heartburn
b. Drowsiness
c. Constipation
d. Bloody sputum

 

 

ANS:  A

The most common symptom of GERD is dyspepsia (heartburn). Other common symptoms include sour or bitter taste; bitter stomach fluid going into the mouth, especially during sleep; hoarseness; water brash (regurgitation of watery acid from the stomach); a repeated need to clear the throat; difficulty swallowing food or liquid; wheezing or coughing at night; and worsening of symptoms after eating or when bending over or lying down.

 

DIF:    Cognitive Level: Remembering        REF:   p. 376

 

  1. Which drug used to treat peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD) is a histamine H2 blocker?
a. Metoclopramide (Reglan)
b. Esomeprazole (Nexium)
c. Famotidine (Pepcid)
d. Cetirizine (Zyrtec)

 

 

ANS:  C

Histamine H2 blockers decrease the secretion of gastric acid. Famotidine is an example of this class of drugs.

 

DIF:    Cognitive Level: Remembering        REF:   p. 379

 

  1. Which activity interferes with the action of histamine H2 blockers?
a. Going to bed late
b. Smoking cigarettes
c. Eating dairy products
d. Taking oral contraceptives

 

 

ANS:  B

Smoking interferes with the action of histamine H2 blockers so encourage patients to quit smoking.

 

DIF:    Cognitive Level: Remembering        REF:   p. 380

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