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Chapter 35: Bone metabolism

Rang & Dale's Pharmacology by Humphrey P. Rang

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Chapter 35: Bone metabolism

 

Complete Chapter Questions With Answers

 

Sample Questions Are Posted Below

 

MULTIPLE CHOICE

  1. Substances that stimulate osteoblasts to express the Receptor Activator of Nuclear factor Kappa B (RANK) ligand include

 

  1. alendronate
  2. raloxifene
  3. fluoride
  4. calcitriol
  5. osteoprotegerin

 

Answer d: calcitriol

 

  1. Which type of vitamin D is formed in the skin by the action of ultraviolet radiation?

 

  1. calcitriol
  2. calcifediol
  3. ergocalciferol
  4. alfacalcidol
  5. cholecalciferol

 

Answer e: cholecalciferol

 

  1. Alendronate is useful in treating osteoporosis because of its ability to

 

  1. stimulate bone formation by osteoblasts
  2. inhibit bone resorption by osteoclasts
  3. block receptor activator of nuclear factor kappa B
  4. cause apoptosis of osteoclasts
  5. cause differentiation of osteoblast precursor cells

 

Answer b: inhibit bone resorption by osteoblasts

 

  1. Activation of calcium-sensing receptors by cinacalcet causes

 

  1. a rise in plasma calcium concentration
  2. increased secretion of parathyroid hormone
  3. decreased secretion of parathyroid hormone
  4. decreased secretion of calcitonin
  5. increased formation of calcitriol

 

Answer c: decreased secretion of parathyroid hormone

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