Chapter 57: Harmful effects of drugs

Chapter 57: Harmful effects of drugs

Complete Chapter Questions With Answers

Sample Questions Are Posted Below

MULTIPLE CHOICE

1. The teratogenic effect of thalidomide usually causes

1. abnormal heart valves
2. mental retardation
3. testicular atrophy
4. absence of long bones of limbs
5. spina bifida

Answer d: absence of long bones of limbs

1. Female offspring of women who received stilbestrol during pregnancy have an increased risk of

1. lung cancer
2. breast cancer
3. vaginal cancer
4. endometrial cancer
5. heart valve defects

Answer c: vaginal cancer

1. The toxic metabolite of paracetamol, N-acetyl-p-benzoquinone imine, is believed to cause liver failure by

1. inhibiting cytochrome P450 enzymes
2. inhibiting lipid peroxidation
3. depleting reactive oxygen species
4. depleting reduced glutathione
5. activating Ca²⁺ ATPases

Answer d: depleting reduced glutathione

1. Which drug may elicit antibodies to the surface of red blood cells and thereby cause hemolytic anemia?

1. methyldopa
2. hydrochlorothiazide
3. propranolol
4. minoxidil
5. clozapine

Answer a: methyldopa